AUTEN-99 hydrobromide

CAS No. 1049780-58-6

AUTEN-99 hydrobromide( AUTEN99 hydrobromide )

Catalog No. M10241 CAS No. 1049780-58-6

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 219 Get Quote
10MG 353 Get Quote
25MG 590 Get Quote
50MG 840 Get Quote
100MG 1143 Get Quote
500MG 2277 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AUTEN-99 hydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
  • Description
    A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy; induces autophagic flux and promotes cell survival in mammalian cell cultures; increases the number of autophagic structures in mice and Drosophila, and effectively penetrates through a blood-brain barrier model; impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson's and Huntington's diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AUTEN99 hydrobromide
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1049780-58-6
  • Formula Weight
    359.285
  • Molecular Formula
    C17H15BrN2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 7.5 mg/mL (20.88 mM)
  • SMILES
    C1CN2C=C(SC2=N1)C3=CC=C(C=C3)C4=CC=CC=C4.Br
  • Chemical Name
    2-([1,1'-biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kovács T, et al. Sci Rep. 2017 Feb 16;7:42014.
molnova catalog
related products
  • Omeprazole

    Omeprazole is a proton pump inhibitor.

  • AUTEN-67

    A small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14; at concentrations of 2, 10, and 100 uM, AUTEN-67 inhibits MTMR14 by nearly 3%, 25%, and 70%, respectively.

  • SJFα

    SJFα (SJF alpha) is a PROTAC formed by an E3 ubiquitin ligase-conjugated protein hydrolysis regulator that degrades p38α and p38δ and can be used in cancer research.